Preventive effect of cyproheptadine hydrochloride in refractory patients with frequent migraine

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Preventive effect of cyproheptadine hydrochloride in refractory patients with frequent migraine

Cyproheptadine hydrochloride (CH) is rarely used to treat adult patients with migraine in Japan because it causes sleepiness. In this study, we investigated the preventive effect of CH in 12 patients who had failed to respond to conventional preventive treatments among 103 migraine patients treated at our hospital. These 12 subjects had all received unsuccessful migraine prophylaxis with lomeri...

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Prophylactic migraine treatment has always been a challenge. Efficacy and tolerability are two main issues in current approved migraine prevention regimens. Since some migraineurs patients fail approved preventative agents, experts are always seeking newer agents. Memantine, a glutaminergic antagonist, could potentially be one of these agents. Objective of current study is assessing the efficac...

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Tolerability and efficacy of memantine as add on therapy in patients with refractory migraine

Prophylactic migraine treatment has always been a challenge. Efficacy and tolerability are two main issues in current approved migraine prevention regimens. Since some migraineurs patients fail approved preventative agents, experts are always seeking newer agents. Memantine, a glutaminergic antagonist, could potentially be one of these agents. Objective of current study is assessing the efficac...

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ژورنال

عنوان ژورنال: SpringerPlus

سال: 2013

ISSN: 2193-1801

DOI: 10.1186/2193-1801-2-573